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Living Donation Discussion and News => Living Donation in the News => Topic started by: Clark on December 10, 2015, 10:51:32 AM
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http://onlinelibrary.wiley.com/doi/10.1111/ajt.13604/abstract (http://onlinelibrary.wiley.com/doi/10.1111/ajt.13604/abstract)
Use of a right lateral sector graft in living donor liver transplantation is feasible, but special caution is needed in respect of the liver anatomy
Takashi Kokudo1, Kiyoshi Hasegawa1, Junichi Arita1, Satoshi Yamamoto1, Junichi Kaneko1, Nobuhisa Akamatsu1, Yoshihiro Sakamoto1, Masatoshi Makuuchi2, Yasuhiko Sugawara1 andNorihiro Kokudo1,*
[size=78%]DOI: 10.1111/ajt.13604[/size]
American Journal of Transplantation
Accepted Article (Accepted, unedited articles published online and citable. The final edited and typeset version of record will appear in future.) (http://onlinelibrary.wiley.com/journal/10.1111/(ISSN)1600-6143/accepted)
Abstract
Right lateral sector (RLS) grafting has been introduced to enlarge the potential donor pool in living donor liver transplantation (LDLT). However, evidence of its feasibility is limited. Data from a total of 437 LDLTs carried out between 2000 and 2013 were analyzed retrospectively. LDLTs using a right liver (RL) graft (n = 251) were compared to those using a RLS graft (n = 28). No donor mortality occurred and the major complication rate was similar between the two groups. The postoperative liver function preservation was better in the RLS graft donors. Concerning the recipients, the mortality and overall survival rates were similar between the two groups. The complication rate in the recipients was higher when more than two arterial or biliary anastomoses were necessary. A systematic literature search identified 4 reports on LDLT using RLS grafts. Among a total of 66 LDLTs including the present series, there were no cases of donor death and the rates of major and minor complications in the donors were 6 and 29%, respectively. The major complications and overall mortality rates in the recipients were 29% and 6%, respectively. LDLT using an RLS graft is feasible, with an acceptable survival rate in the recipients.