Living Donors Online Message Board
Living Donation Discussion and News => Living Donation in the News => Topic started by: Clark on August 01, 2013, 11:07:42 AM
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http://www.atcmeetingabstracts.com/abstract/increasing-hla-dr-mismatches-is-associated-with-inferior-kidney-allograft-outcome-in-low-immune-risk-living-donor-kidney-transplant-recipients/
Increasing HLA DR Mismatches Is Associated with Inferior Kidney Allograft Outcome in Low Immune Risk Living Donor Kidney Transplant Recipients
S. Lynch, K. Tinckam, J. Kim
Background: HLA DR mismatches (MM) have been shown to negatively influence kidney allograft outcomes in historical cohorts. We examined whether this effect persists in the modern era of kidney transplantation in low immune risk living donor kidney transplant recipients.
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Conclusion: In a contemporary cohort of low immune risk, living donor KTR, HLA DR MM remains as an independent predictor of graft failure. HLA DR MM may be a relevant consideration in allocation algorithms and risk assessment in low immune risk KTR.