https://pubmed.ncbi.nlm.nih.gov/40523265/ (https://pubmed.ncbi.nlm.nih.gov/40523265/)Cadaveric Penile Microdissection and its Impact on Live Donor Penile Transplantation: an Experimental Case Series Study
Miroslav L Djordjevic (https://pubmed.ncbi.nlm.nih.gov/?term=Djordjevic+ML&cauthor_id=40523265) et al.
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[/size] [size=78%][/size][size=78%]2025 Sep-Oct;51(5):e20250195. [/size][size=78%][/color]doi: 10.1590/S1677-5538.IBJU.2025.0195.[/size][size=78%][/color] DOI: [/size][size=78%]10.1590/S1677-5538.IBJU.2025.0195 (https://doi.org/10.1590/s1677-5538.ibju.2025.0195)[/size]
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Abstract
Purpose: We evaluated the possibility of using remaining penile tissue such as preserved corpora cavernosa, the remaining glans tissue with neurovascular components and the anterior urethra, after femininizing gender affirmation surgery for live donor penile transplantation.
Materials and methods: Between January 2022 and January 2024, penile dissection was performed in 31 male cadavers, aged 20-59 years (mean 42 years). The dissection with tissue preservation was based on penile disassembly principles: penile skin, part of the glans with neurovascular elements, and proximal urethra were prepared for feminizing genitoplasty while remaining penile tissue such as full corpora cavernosa, glans and anterior urethra were micro dissected and properly measured.
Results: Mean penile length was 10.24 cm in the flaccid and 14.6 cm in the stretched state. The mean diameters of the deep dorsal vein and the right and left arteries were measured at 2.8 mm, 1.9 mm and 1.8 mm, respectively. Penile nerves with an anatomical distribution were found in all cases. The mean length and girth of cavernosum bodies were 19.24 cm, and 7.29 cm, respectively. The mean length of the distal urethra was 15.73 cm (range 11-21 cm), without registered anomalies. The mean volume of the glans after neoclitoris creation was 89% of total. All dissections were completed successfully, and all entities were joined again in all cadavers.
Conclusions: The cadaveric study has confirmed the technical feasibility and possibilities of using all remaining penile tissue for possible live donor penile transplantation.Keywords: Gender-Affirming Surgery; Penis; Transplantation.
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