| LDO Home | General | Kidney | Liver | Marrow | Experiences | Buddies | Hall of Fame | Calendar | Contact Us |

Author Topic: The first successful case of ABO-incompatible living-donor lobar lung transplant  (Read 2803 times)

0 Members and 1 Guest are viewing this topic.

Offline Clark

  • Administrator
  • Top 10 Poster!
  • *****
  • Posts: 3,050
  • Please give the gift of life!
    • Living Donors Online!
https://www.amjtransplant.org/article/S1600-6135(23)00457-4/fulltext

CASE REPORT| VOLUME 23, ISSUE 9, P1451-1454, SEPTEMBER 2023

The first successful case of ABO-incompatible living-donor lobar lung transplantation following desensitization therapy

      Daisuke Nakajima

Itsuki Yuasa
Hidenao Kayawake


      Shiro Baba
Hidefumi Hiramatsu
Hiroshi Date
et al.

American Journal of Transplantation
Published:May 04, 2023

DOI:https://doi.org/10.1016/j.ajt.2023.04.031

Abstract
ABO-incompatible (ABO-I) living-donor lobar lung transplantation (LDLLT) was successfully performed in a 14-year-old girl who suffered from bronchiolitis obliterans due to graft-versus-host disease following hematopoietic stem cell transplantation. In the ABO-I LDLLT procedure, the blood type O patient received a right lower lobe donated from her blood type B father and a left lower lobe donated from her blood type O mother. Desensitization therapy, using rituximab, immunosuppressants, and plasmapheresis, was implemented for 3 weeks prior to transplantation to reduce the production of anti-B antibodies in the recipient and prevent acute antibody-mediated rejection after ABO-I LDLLT.
Unrelated directed kidney donor in 2003, recipient and I both are well.
629 time blood and platelet donor since 1976 and still giving!
Elected to the OPTN/UNOS Boards of Directors & Executive, Kidney Transplantation, and Ad Hoc Public Solicitation of Organ Donors Committees, 2005-2011
Proud grandpa!

 

Copyright © International Association of Living Organ Donors, Inc. All Rights Reserved