I actually took part in a research project before and after my donation. The study was in regards to depression after organ donation surgery. They told me some people can go on an emotional high after a donation (probably because they feel good about what they did and are receiving a lot of attention). This can be followed by depression (probably a result of the shock to the body, medications, staying in the hospital, worrying about complications and decrease in the amount of attention). Personally, I didn't go through an emotional high and I didn't think at the time I went through a depression. But looking back, I was very frustrated following the surgery. I initially had some minor complications. Also, I am a very active individual and was very frustrated by my inability to do what I was used to doing as well as I found the fatigue that follows the surgery was frustrating for me. Was I depressed, maybe mild depression but nothing too bad. But if you have a history or are predisposed to depression, it would be a good idea to be open about it with the coordinators. Also, post surgery, it would be a good idea to proactively treat depression if you feel depressed. Good luck.