Role of Estimated GFR CKD-EPI as Screening Tool for Donor Selection

[Clark]

http://www.atcmeetingabstracts.com/abstract/role-of-estimated-gfr-ckd-epi-as-screening-tool-for-donor-selection/

Role of Estimated GFR CKD-EPI as Screening Tool for Donor Selection
S. Fernandez, S. Mohan, Z. Zaky, J. Crew, G. Dube, J. Wexler, M. Carrol, L. Ratner, D. Cohen, B. Tanriover

Purpose: Living donor selection usually includes a measured renal function rather than estimated GFR (eGFR) equations, such as CKD-EPI because of concerns of accuracy. However, at Columbia University Medical Center, we use an eGFR threshold of 100 ml/min as a screening tool to identify patients who need to have their measured renal function to avoid using potential donors with renal function of < 80 ml/min/1.73m2.

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Conclusion: Our results suggest that the use of a high threshold of eGFR such as 100mL/min in the evaluation of donors decreases the need for measurement of renal function in all donors while at the same time limiting the risk of kidney donation from subjects with suboptimal renal function.