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Living Donation Forum / Re: Severe Nerve Pain in Tesicular area
« Last post by jennaride on November 13, 2022, 03:47:13 AM »
Nice ressource clark thank you!
Living Donation Forum / Re: Newbie Here - Liver Donor
« Last post by Moozake_w on November 10, 2022, 05:36:54 PM »
Hi all, em a newbie here. Hoping that i will have good experience with this forum.

Exclusion of race may lead to classification of living kidney donor as having CKD
ByKristine Houck, MA, ELS
Fact checked byGina Brockenbrough, MA

Use of the 2021 Chronic Kidney Disease Epidemiology Collaboration eGFR formula may lead to incorrect classification of Black living kidney donors as having CKD, according to data presented here.
“The final messaging for this is the new eGFR, that is a race-neutral eGFR. One has to understand what it really means. No equation is perfect. In trying to correct one issue, we may unintentionally generate another issue,” Vineeta Kumar, MD, from the University of Alabama at Birmingham, told Healio Nephrology. “If you aren’t aware of it, we can do disservice to the very patients we are wanting to help.”
Kumar and colleagues used a national database to identify 63,246 living kidney donors with pre-donation eGFR greater than 60 mL/min/1.73 m2. Overall, 11.2% of the living kidney donors were Black with a mean creatinine of 0.88 mg/dL.
Kumar and colleagues found that the eGFR of Black living kidney donors was 109.7 mL/min/1.73 m2 and 97.7 mL/min/1.73 m2 when using the 2009 and 2021 formulas, respectively. Additionally, 17.7% of Black living kidney donors had been reclassified with higher pre-donation CKD stages when the 2021 formula was used.
Of the 44,525 living kidney donors who had more than two creatinine measurements taken after their kidney donations, 9.3% of the patients were Black with mean creatinine of 1.24 mg/dL. The mean eGFR for Black living kidney donors was 73.2 mL/min/1.73 m2 and 65.6 mL/min/1.73 m2 when using the 2009 and 2021 formulas, respectively. Additionally, 25.5% of Black living kidney donors had been reclassified with a higher pre-donation CKD stage when the 2021 formula was used.
“Estimated GFRs are never perfect. They are never going to be a ‘one size fits all’ for everybody. We have to inform it with additional understanding, so that is more education. Then transition, when there is a question, from estimated to measured eGFRs,” Kumar said.
Living Donation Forum / Re: How Much Water Should You Drink?
« Last post by Michael on September 27, 2022, 01:35:00 PM »
There was also a 2004 study into this question, as well as the right levels of sodium and potassium, which are also important considerations for kidney health. A summary of that study can be found here (and it has a link to the full study): https://www.nationalacademies.org/news/2004/02/report-sets-dietary-intake-levels-for-water-salt-and-potassium-to-maintain-health-and-reduce-chronic-disease-risk

Living Donation Forum / How Much Water Should You Drink?
« Last post by Michael on September 26, 2022, 12:27:49 PM »
How much water should someone drink? It's a common question, especially among recent kidney donors. I ran across this 19-minute podcast that shares the latest information on this topic, and dispels common myths: https://www.npr.org/2022/09/20/1124133408/water-water-everywhere-but-how-much-do-you-really-need
Living Donation Forum / Re: Living kidney donor blood type O+
« Last post by Michelle on September 12, 2022, 08:03:37 PM »

I know it's been a while since you posted, but I'm new to this forum. If your friend is still willing to donate, I'm very much interested! O blood type would be perfect as that's an universal donor.

The American Liver Foundation and UPMC have launched a new, five-part animated video series to help liver transplant patients find a living donor. A recent addition to a comprehensive Living Donor Liver Transplant Information Center launched in 2020, the newly created video series helps patients and families easily understand the steps they can take to help find a living donor.
Full disclosure: I underwent this procedure in 2003, so my surgery must be one of these. As a white male, at the time 44 years old, and at the time a BMI of 23. I believe my abdominal issues since then are not a result of surgical complications, whoever the state of being a donor with one kidney has affected medical decision making about appropriate treatment options and recommendations, and changed the risk profiles for the conditions I have experienced, considered normal changes due to aging.

Complications After Hand-Assisted Laparoscopic Living Donor Nephrectomy
Author links open overlay panel
Xiomara Benavides


To study the complications of hand-assisted laparoscopic living donor nephrectomy (HALLDN) with an emphasis on complications occurring early after hospital discharge up to 120 days after surgery.
Patients and Methods
We retrospectively categorized complications using the Clavien-Dindo classification in 3002 HALLDNs performed at 1 center from January 1, 2000, through December 31, 2019. In addition to overall summaries, modeling was used to identify correlates of complications before and after living donation.

Of these donors, 87% were White, 59% were female, the mean age was 45 years (range, 18-77 years), 30.3% had a body mass index of at least 30, and 36.3% had previous abdominopelvic surgery. There were no deaths related to the surgery. The incidence of major complications (intraoperative complications plus Clavien-Dindo grade ≥III postoperatively) was 2.5% (n=74). The overall complication rate was 12.4% (n=371), including 15 intraoperative, 76 postoperative before discharge, and 280 after discharge to 120 days. Reoperation was required in 1.8% of patients (n=54), and all but 1 of these were incision-related problems. Seventy-six percent of all complications occurred after discharge, including 85% of the reoperations. For major complications, no risk factor was found. Risk factors for any complication included paramedian incision (hazard ratio

, 2.54; 95% CI, 1.49 to 4.34; P<.001); a history of abdominopelvic surgery (HR, 1.37; 95% CI, 1.07 to 1.76; P=.01), male sex (HR, 1.37; 95% CI, 1.07 to 1.76; P=.01), non-White race (HR, 1.40; 95% CI, 1.05 to 1.88; P=.02), and early era of the experience.[/font][/size]

Most major complications of HALLDN occur after discharge, suggesting that close follow-up is warranted and that the current literature may underestimate the true incidence.

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