- Welcome to Living Donors Online Message Board.
By and For Living Donors
Recent posts
#31
Using the Message Board / Re: Living Donors on Facebook
Last post by Michael - September 19, 2025, 01:21:03 PMThe LDO Facebook Group has been closed and replaced by a Facebook Page that you can find here: https://www.facebook.com/profile.php?id=61579185672724
#32
Living Donation Forum / We Have a New Facebook Page!
Last post by Michael - September 02, 2025, 08:13:44 AMAfter 12 years as a Facebook Group, we decided that the format of a Facebook Page is more appropriate for what we do. Therefore, we have closed the Group and replaced it with the "Living Donors Online" Facebook Page. You can find it here: https://www.facebook.com/profile.php?id=61579185672724
Please visit the Page and "Like" it so you can stay in touch. Thanks!
Michael
Please visit the Page and "Like" it so you can stay in touch. Thanks!
Michael
#33
Living Donation Forum / Re: September 2025 Living Dono...
Last post by Michael - September 02, 2025, 08:02:36 AMThanks for the acknowledgement! Yes, it's been 25 years since LDO started, and it's been a long and winding road.
A special "thank you" to you, John, for all you've done and continue to do to educate, support, and advocate for living donors!
A special "thank you" to you, John, for all you've done and continue to do to educate, support, and advocate for living donors!
#34
Living Donation in the News / india: More Women Than Men Ple...
Last post by Clark - September 01, 2025, 06:56:52 PMhttps://www.hercircle.in/engage/get-inspired/trending/more-women-than-men-pledge-to-donate-their-organs-when-applying-for-a-driverrsquos-license-9550.html
More Women Than Men Pledge To Donate Their Organs When Applying For A Driver's License
Not only do women make up the majority of living organ donors, but statistics also indicate that they outnumber men in terms of the percentage of applicants for driving licenses with the pledge to donate their organs in the event of a fatal accident. When applying for a driver's license, the Ministry of Road Transport and Highways introduced a provision to pledge for organ donation in the event of death.
...
More Women Than Men Pledge To Donate Their Organs When Applying For A Driver's License
Not only do women make up the majority of living organ donors, but statistics also indicate that they outnumber men in terms of the percentage of applicants for driving licenses with the pledge to donate their organs in the event of a fatal accident. When applying for a driver's license, the Ministry of Road Transport and Highways introduced a provision to pledge for organ donation in the event of death.
...
#35
Living Donation in the News / Factors Associated With Willin...
Last post by Clark - September 01, 2025, 03:05:58 PMhttps://www.researchgate.net/publication/394697939_Factors_Associated_With_Willingness_to_Become_a_Living_Organ_Donor
Factors Associated With Willingness to Become a Living Organ Donor August 2025JAMA Network Open 8(8):e2527592DOI:10.1001/jamanetworkopen.2025.27592
Taranika Sarkar Das, et al.
Abstract
Importance
Organ transplant demand in the US far exceeds supply. Living donor organ transplantation (LDOT) offers a critical solution to reducing this shortage, yet its adoption remains limited. Understanding factors that influence willingness to donate is essential for expanding the living donor pool.
Objective
To examine whether knowledge of LDOT, perceptions of fairness in the transplant system, geography, socioeconomic status, and religiosity are associated with individuals' willingness to become living organ donors.
Design, Setting, and Participants
This cross-sectional study analyzed responses from the 2019 National Survey of Organ Donation Attitudes and Practices (NSODAP). Participants were aged 18 years or older. Poststratification weights were applied to align the sample with US census demographic characteristics. Data were analyzed from November 2024 through May 2025.
Exposures
Socioeconomic status, region of residence, knowledge of living donation, perceptions of inequality in transplantation, and religiosity.
Main Outcome and Measures
The primary outcome was the self-reported likelihood of donating an organ to a family member while living. Composite scores were created to assess knowledge about living donation, perceptions of fairness in organ transplantation, and religiosity. Multivariable logistic regression was performed to evaluate associations with willingness to donate, adjusting for demographic and socioeconomic factors.
Results
Of the 9922 survey respondents, 5264 (53.2%) were women, and 7801 (78.9%) reported an educational level of postsecondary training or above. The largest proportion of participants was aged 18 to 34 years (3006 [32.6%]), followed by 50 to 64 years (2390 [25.9%]), and most had health insurance (8547 [86.1%]); 8667 (87.4%) reported being likely to donate. Women were more likely to report willingness to donate than men (odds ratio [OR], 1.49; 95% CI, 1.23-1.81; P < .001), and Asian participants were less likely to report willingness to donate than White participants (OR, 0.72; 95% CI, 0.55-0.94; P = .02). Higher knowledge scores were associated with increased willingness to donate (OR, 1.62; 95% CI, 1.49-1.77; P < .001), while lower perceptions of fairness in organ allocation were associated with decreased willingness (OR, 0.85; 95% CI, 0.78-0.92; P < .001). Conclusions and Relevance In this cross-sectional study analyzing survey data from NSODAP, willingness to become a living organ donor was associated with knowledge, perceptions of fairness within the organ transplant system, and socioeconomic factors. The findings suggest that targeted education and transparency in organ allocation policies may help expand the US living donor pool.
Factors Associated With Willingness to Become a Living Organ Donor August 2025JAMA Network Open 8(8):e2527592DOI:10.1001/jamanetworkopen.2025.27592
Taranika Sarkar Das, et al.
Abstract
Importance
Organ transplant demand in the US far exceeds supply. Living donor organ transplantation (LDOT) offers a critical solution to reducing this shortage, yet its adoption remains limited. Understanding factors that influence willingness to donate is essential for expanding the living donor pool.
Objective
To examine whether knowledge of LDOT, perceptions of fairness in the transplant system, geography, socioeconomic status, and religiosity are associated with individuals' willingness to become living organ donors.
Design, Setting, and Participants
This cross-sectional study analyzed responses from the 2019 National Survey of Organ Donation Attitudes and Practices (NSODAP). Participants were aged 18 years or older. Poststratification weights were applied to align the sample with US census demographic characteristics. Data were analyzed from November 2024 through May 2025.
Exposures
Socioeconomic status, region of residence, knowledge of living donation, perceptions of inequality in transplantation, and religiosity.
Main Outcome and Measures
The primary outcome was the self-reported likelihood of donating an organ to a family member while living. Composite scores were created to assess knowledge about living donation, perceptions of fairness in organ transplantation, and religiosity. Multivariable logistic regression was performed to evaluate associations with willingness to donate, adjusting for demographic and socioeconomic factors.
Results
Of the 9922 survey respondents, 5264 (53.2%) were women, and 7801 (78.9%) reported an educational level of postsecondary training or above. The largest proportion of participants was aged 18 to 34 years (3006 [32.6%]), followed by 50 to 64 years (2390 [25.9%]), and most had health insurance (8547 [86.1%]); 8667 (87.4%) reported being likely to donate. Women were more likely to report willingness to donate than men (odds ratio [OR], 1.49; 95% CI, 1.23-1.81; P < .001), and Asian participants were less likely to report willingness to donate than White participants (OR, 0.72; 95% CI, 0.55-0.94; P = .02). Higher knowledge scores were associated with increased willingness to donate (OR, 1.62; 95% CI, 1.49-1.77; P < .001), while lower perceptions of fairness in organ allocation were associated with decreased willingness (OR, 0.85; 95% CI, 0.78-0.92; P < .001). Conclusions and Relevance In this cross-sectional study analyzing survey data from NSODAP, willingness to become a living organ donor was associated with knowledge, perceptions of fairness within the organ transplant system, and socioeconomic factors. The findings suggest that targeted education and transparency in organ allocation policies may help expand the US living donor pool.
#36
Living Donation in the News / Comparative analysis of outcom...
Last post by Clark - September 01, 2025, 02:41:34 PMhttps://www.researchgate.net/journal/PLOS-One-1932-6203/publication/394973980_Comparative_analysis_of_outcomes_in_high_KDPI_spectrum_kidney_transplants_using_unsupervised_machine_learning_algorithm/links/68adfc742c7d3e0029b3b0f7/Comparative-analysis-of-outcomes-in-high-KDPI-spectrum-kidney-transplants-using-unsupervised-machine-learning-algorithm.pdf?origin=journalDetail
Comparative analysis of outcomes in high KDPI spectrum kidney transplants using unsupervised machine learning algorithm
Mahmoudreza Moein, et al.
PLoS One 20(8): e0324265. https://doi.org/10.1371/journal.pone.0324265
Abstract
Background
The Kidney Donor Profile Index (KDPI) is a continuous metric used to estimate the risk of allograft failure for kidneys from deceased donors. Lower KDPI scores are associated with longer post-transplant kidney function. This study aims to evaluate the outcomes of kidney transplantation using high-KDPI kidneys (98–100%) compared to those with moderately high KDPI scores (85–97%), employing a novel case-matching approach using machine learning.
Methods
We conducted a retrospective analysis of the United Network for Organ Sharing (UNOS) database, examining kidney transplants performed in the United States between January 2000 and May 2020. An unsupervised machine learning algorithm was used to match recipients of KDPI 98–100% kidneys with recipients of KDPI 85–97% kidneys based on key baseline characteristics, including recipient age, body mass index (BMI), cold ischemia time, HLA mismatch, ethnicity, and gender.
Results
A total of 6,624 matched cases were selected for analysis. The mean follow-up duration was 4.5 years for the KDPI 98–100% cohort and 4.6 years for the KDPI 85–97% cohort. The five-year allograft survival was 51.7% for the KDPI 98–100% group versus 58% for the KDPI 85–97% group (P<0.001). Asian recipients showed the highest survival in both cohorts (68% vs. 69%). Donation after circulatory death (DCD) status did not significantly impact outcomes. Across the full cohort, 1,819 cases of allograft failure were recorded, with chronic rejection being the leading cause (28.4% vs. 30%, P=0.56).
Conclusion
Transplantation with high-KDPI kidneys, though associated with lower survival rates, remains a viable option for expanding the donor pool. With appropriate recipient selection, high-KDPI kidneys can improve patient quality of life, reduce wait times, and lower healthcare costs. Our findings support a more nuanced approach to organ allocation using advanced matching strategies.
Comparative analysis of outcomes in high KDPI spectrum kidney transplants using unsupervised machine learning algorithm
Mahmoudreza Moein, et al.
PLoS One 20(8): e0324265. https://doi.org/10.1371/journal.pone.0324265
Abstract
Background
The Kidney Donor Profile Index (KDPI) is a continuous metric used to estimate the risk of allograft failure for kidneys from deceased donors. Lower KDPI scores are associated with longer post-transplant kidney function. This study aims to evaluate the outcomes of kidney transplantation using high-KDPI kidneys (98–100%) compared to those with moderately high KDPI scores (85–97%), employing a novel case-matching approach using machine learning.
Methods
We conducted a retrospective analysis of the United Network for Organ Sharing (UNOS) database, examining kidney transplants performed in the United States between January 2000 and May 2020. An unsupervised machine learning algorithm was used to match recipients of KDPI 98–100% kidneys with recipients of KDPI 85–97% kidneys based on key baseline characteristics, including recipient age, body mass index (BMI), cold ischemia time, HLA mismatch, ethnicity, and gender.
Results
A total of 6,624 matched cases were selected for analysis. The mean follow-up duration was 4.5 years for the KDPI 98–100% cohort and 4.6 years for the KDPI 85–97% cohort. The five-year allograft survival was 51.7% for the KDPI 98–100% group versus 58% for the KDPI 85–97% group (P<0.001). Asian recipients showed the highest survival in both cohorts (68% vs. 69%). Donation after circulatory death (DCD) status did not significantly impact outcomes. Across the full cohort, 1,819 cases of allograft failure were recorded, with chronic rejection being the leading cause (28.4% vs. 30%, P=0.56).
Conclusion
Transplantation with high-KDPI kidneys, though associated with lower survival rates, remains a viable option for expanding the donor pool. With appropriate recipient selection, high-KDPI kidneys can improve patient quality of life, reduce wait times, and lower healthcare costs. Our findings support a more nuanced approach to organ allocation using advanced matching strategies.
#37
Living Donation in the News / King approves awarding King Ab...
Last post by Clark - September 01, 2025, 02:30:45 PMhttps://saudigazette.com.sa/article/654520/SAUDI-ARABIA/King-approves-awarding-King-Abdulaziz-Medal-to-200-Saudi-organ-donors
King approves awarding King Abdulaziz Medal to 200 Saudi organ donors
Custodian of the Two Holy Mosques King Salman has approved awarding the King Abdulaziz Medal of the Third Class to 200 Saudi male and female citizens who have donated their organs.
King approves awarding King Abdulaziz Medal to 200 Saudi organ donors
Custodian of the Two Holy Mosques King Salman has approved awarding the King Abdulaziz Medal of the Third Class to 200 Saudi male and female citizens who have donated their organs.
#38
Living Donation in the News / Xenotransplantation: Scientist...
Last post by Clark - September 01, 2025, 02:21:20 PMhttps://www.nature.com/articles/s41591-025-03861-x
https://singularityhub.com/2025/08/28/in-a-first-scientists-transplant-a-modified-pig-lung-into-a-person/
In a First, Scientists Transplant a Modified Pig Lung Into a Person
https://singularityhub.com/2025/08/28/in-a-first-scientists-transplant-a-modified-pig-lung-into-a-person/
In a First, Scientists Transplant a Modified Pig Lung Into a Person
#39
Living Donation in the News / India: Couple Dies After Woman...
Last post by Clark - September 01, 2025, 02:16:19 PMhttps://www.timesnownews.com/health/couple-dies-after-woman-donates-liver-to-husband-what-to-know-about-post-transplant-recovery-article-152543701
Couple Dies After Woman Donates Liver to Husband: What to Know About Post-Transplant Recovery
Authored by:
Ashima Sharda Mahindra
A couple from Pune died days after the wife donated part of her liver to the 45-year-old husband, who went into a fatal cardiogenic shock after the surgery. According to doctors, the woman's death is attributed to septic shock and multi-organ failure. The case highlights the importance of understanding post-transplant recovery, including risks, complications, and critical care needed after such major surgeries.
A woman donor from Pune died days after her husband passed away following liver transplant surgery last week, doctors said. The 45-year-old man, identified as Bapu Komkar, underwent the surgery after Kamini donated a part of her liver. According to doctors, Bapu suffered a post-operative cardiogenic shock, and Kamini's death is attributed to septic shock and multi-organ failure.
News reports say Maharashtra's health department has issued a formal notice demanding all procedural and medical details from the hospital to investigate the incident thoroughly.
Husband suffered from end-stage liver cirrhosis
Doctors say Bapu was suffering from end-stage liver cirrhosis, and Kamini had volunteered as a live donor. However, according to the hospital, a thorough pre-surgical counselling risk was provided to the couple. After the surgery, Bapu's condition deteriorated rapidly, and he succumbed.
While Kamini did show signs of recovery initially, she later developed septic shock and, despite all efforts, could not be saved.
What is cardiogenic shock?
A cardiogenic or hypotensive shock happens when your body's circulatory system fails to move oxygenated blood and nutrients to cells, leading to multi-organ failure despite advanced treatment.
Experts say it is a medical emergency characterized by a dangerously low cardiac output, which causes inadequate blood flow to vital organs. It is commonly caused by a severe heart attack, but other heart conditions can also lead to it.
Why is an organ transplant done?
According to doctors, organ transplantation is done to save lives when vital organs like the heart, liver, kidneys, lungs, or pancreas begin to fail or have stopped working due to illness, injury, or genetic conditions. The procedure replaces the non-functioning organ with a healthy one from a donor, with matching of the same blood group, and offers a chance to extend life and improve the patient's quality of life.
While organ donation and transplantation save many lives across the world every year, it is important to understand that living organ donors undertake a greater risk of having surgery than those who have passed. Also, sometimes, organ transplants fail, or the recipient's body rejects the organ after the transplant.
What is post-transplant recovery?
According to doctors, post-transplant recovery involves carefully following schedules of medicine, a healthy diet, and slowly taking care of physical health after any operation. Early ambulation, monitoring vital signs like temperature and blood pressure, and attending frequent follow-up appointments are also essential for monitoring the new organ's function and managing overall health.
Liver transplant is among the riskiest surgeries, as the patient's recovery would be lifelong and needs adherence to prescribed immunosuppressant medications so that there is no organ rejection. Also, doctors suggest a healthy and balanced diet, avoiding harmful substances like alcohol and tobacco, and gradual physical activity as advised by doctors.
Key aspects of recovery also include good hygiene, which can help prevent infections; regular follow-up appointments for monitoring; and prompt reporting of any new symptoms like fever or jaundice to your transplant team. At the hospital, specialised equipment will be there to monitor your recovery, providing fluids and medications through tubes and drips until you can breathe independently and fluid balance is stable. Mostly, doctors will discharge you when your pain is controlled, you drink and eat well, and can walk with minimal difficulty.
Couple Dies After Woman Donates Liver to Husband: What to Know About Post-Transplant Recovery
Authored by:
Ashima Sharda Mahindra
A couple from Pune died days after the wife donated part of her liver to the 45-year-old husband, who went into a fatal cardiogenic shock after the surgery. According to doctors, the woman's death is attributed to septic shock and multi-organ failure. The case highlights the importance of understanding post-transplant recovery, including risks, complications, and critical care needed after such major surgeries.
A woman donor from Pune died days after her husband passed away following liver transplant surgery last week, doctors said. The 45-year-old man, identified as Bapu Komkar, underwent the surgery after Kamini donated a part of her liver. According to doctors, Bapu suffered a post-operative cardiogenic shock, and Kamini's death is attributed to septic shock and multi-organ failure.
News reports say Maharashtra's health department has issued a formal notice demanding all procedural and medical details from the hospital to investigate the incident thoroughly.
Husband suffered from end-stage liver cirrhosis
Doctors say Bapu was suffering from end-stage liver cirrhosis, and Kamini had volunteered as a live donor. However, according to the hospital, a thorough pre-surgical counselling risk was provided to the couple. After the surgery, Bapu's condition deteriorated rapidly, and he succumbed.
While Kamini did show signs of recovery initially, she later developed septic shock and, despite all efforts, could not be saved.
What is cardiogenic shock?
A cardiogenic or hypotensive shock happens when your body's circulatory system fails to move oxygenated blood and nutrients to cells, leading to multi-organ failure despite advanced treatment.
Experts say it is a medical emergency characterized by a dangerously low cardiac output, which causes inadequate blood flow to vital organs. It is commonly caused by a severe heart attack, but other heart conditions can also lead to it.
Why is an organ transplant done?
According to doctors, organ transplantation is done to save lives when vital organs like the heart, liver, kidneys, lungs, or pancreas begin to fail or have stopped working due to illness, injury, or genetic conditions. The procedure replaces the non-functioning organ with a healthy one from a donor, with matching of the same blood group, and offers a chance to extend life and improve the patient's quality of life.
While organ donation and transplantation save many lives across the world every year, it is important to understand that living organ donors undertake a greater risk of having surgery than those who have passed. Also, sometimes, organ transplants fail, or the recipient's body rejects the organ after the transplant.
What is post-transplant recovery?
According to doctors, post-transplant recovery involves carefully following schedules of medicine, a healthy diet, and slowly taking care of physical health after any operation. Early ambulation, monitoring vital signs like temperature and blood pressure, and attending frequent follow-up appointments are also essential for monitoring the new organ's function and managing overall health.
Liver transplant is among the riskiest surgeries, as the patient's recovery would be lifelong and needs adherence to prescribed immunosuppressant medications so that there is no organ rejection. Also, doctors suggest a healthy and balanced diet, avoiding harmful substances like alcohol and tobacco, and gradual physical activity as advised by doctors.
Key aspects of recovery also include good hygiene, which can help prevent infections; regular follow-up appointments for monitoring; and prompt reporting of any new symptoms like fever or jaundice to your transplant team. At the hospital, specialised equipment will be there to monitor your recovery, providing fluids and medications through tubes and drips until you can breathe independently and fluid balance is stable. Mostly, doctors will discharge you when your pain is controlled, you drink and eat well, and can walk with minimal difficulty.
#40
Living Donation in the News / AI Platform helps UNOS fulfill...
Last post by Clark - September 01, 2025, 02:01:57 PMhttps://www.servicenow.com/customers/unos.html
UNOS fulfills its life-saving mission
The ServiceNow AI Platform helps nonprofit coordinate thousands of life-saving organ transplants each year...
UNOS fulfills its life-saving mission
The ServiceNow AI Platform helps nonprofit coordinate thousands of life-saving organ transplants each year...