Increasing HLA DR Mismatches Is Associated with Inferior Kidney Allograft Outcom

[Clark]

http://www.atcmeetingabstracts.com/abstract/increasing-hla-dr-mismatches-is-associated-with-inferior-kidney-allograft-outcome-in-low-immune-risk-living-donor-kidney-transplant-recipients/

Increasing HLA DR Mismatches Is Associated with Inferior Kidney Allograft Outcome in Low Immune Risk Living Donor Kidney Transplant Recipients
S. Lynch, K. Tinckam, J. Kim

Background: HLA DR mismatches (MM) have been shown to negatively influence kidney allograft outcomes in historical cohorts. We examined whether this effect persists in the modern era of kidney transplantation in low immune risk living donor kidney transplant recipients.

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Conclusion: In a contemporary cohort of low immune risk, living donor KTR, HLA DR MM remains as an independent predictor of graft failure. HLA DR MM may be a relevant consideration in allocation algorithms and risk assessment in low immune risk KTR.